El grupo de Física Estadística y de los Sistemas Complejos les invita al siguiente seminario. Ponente: Jorge F. Mejías. University of Amsterdam. Title: Mechanisms of distributed working memory in the brain Abstract: Working memory is defined as the ability of the brain to retain and manipulate information over short periods of time. While traditionally associated with persistent neural firing in prefrontal cortex, mounting evidence suggests that neural correlates of working memory can be found across multiple cortical areas beyond prefrontal cortex, and often with simultaneous multi-area activation patterns. However, the origin of such distributed working memory activity is at the moment not understood. In this talk, I will present a novel mechanism based on long-range activity reverberation that supports the emergence of large-scale persistent activity patterns across the cortex. These patterns encode and retain selective information distributed across multiple cortical areas, and emerge even in situations in which the classical working memory model based on local synaptic reverberation is ineffective. The mechanism is implemented on an anatomically constrained large-scale network of the macaque cortex and leads to experimentally testable predictions on the size and activity profile of the distributed attractors, the strength of local synaptic connections, the effect of distractors in working memory tasks, and the consequences of area-specific lesions. Fecha y hora: Viernes 10 de Mayo. 11:00. Lugar: Seminario de informática del Área de Física de la Materia. Planta baja del edificio de Física. Facultad de Ciencias. Atentamente, --------------------------------------------------------------------------------- Daniel Manzano Electromagnetism and Condensed Matter Department University of Granada Facultad de Ciencias, Av. Fuentenueva s/n Granada 18071, Spain Phone: +34 958241000 Ext: 20569 http://ic1.ugr.es/manzano/ http://ic1.ugr.es/manzano/